Hormones and hair growth

  Hair loss in a causal relationship to thyroid disorders is well documented July 2010

Abstract With respect to the relationship between , the role of androgens for androgenetic alopecia (AGA) and hirsutism is best acknowledged.

Accordingly, therapeutic strategies that intervene in androgen metabolism have been successfully developed for treatment of these conditions.

Clinical observations of hair conditions involving hormones beyond the androgen horizon have determined their role in regulation of hair growth: estrogens, prolactin, thyroid hormone, cortisone, growth hormone (GH), and melatonin.

Primary GH resistance is characterized by thin hair, while acromegaly may cause hypertrichosis. Hyperprolactinemia may cause hair loss and hirsutism.

Partial synchronization of the hair cycle in anagen during late pregnancy points to an estrogen effect, while aromatase inhibitors cause hair loss.

Hair loss in a causal relationship to thyroid disorders is well documented. In contrast to AGA, senescent alopecia affects the hair in a diffuse manner.

The question arises, whether the hypothesis that a causal relationship exists between the age-related reduction of circulating hormones and organ function also applies to hair and the aging of hair.
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Minoxidil in hair growth items

  Such products are not allowed to contain western medicinal ingredients July 2010

Two products used by Beijing 101 Hair Consultants have been found to contain an undeclared western medicinal ingredient by the Health Sciences Authority (HSA). These two products are labelled to "promote hair growth, reduce hair loss and improve blood circulation".

"Hair Growth Formula D-2653-B" and "Hair Growth Tonic E-0583-D" are regulated as Chinese Proprietary Medicines (CPM) and declared to contain natural herbs. Such products are not allowed to contain western medicinal ingredients or substances controlled under the Poisons Act.

However, one batch of "Hair Growth Formula D-2653-B" (B/N 20091201) and "Hair Growth Tonic E-0583-D" (B/N 20091201) were found to contain the western medicinal ingredient minoxidil during HSA's regular product quality sampling programme. The affected batches of the two products, which were manufactured by Beijing Zhangguang 101 Science & Technology Development Co. Ltd in Beijing, China, have been recalled from Beijing 101 haircare centres.

Minoxidil is classified as a pharmacy-only medicine and is used to treat hair loss. Some of the side effects of using topical preparations containing this medicine include rashes, skin irritation, itching and exacerbation of hair loss in susceptible individuals.

HSA urges those who have purchased the affected batch of the products to stop using them. Those who develop any unexpected reactions to these products are advised to seek medical advice.

"HSA has licensed only two medicinal ingredients that have been proven scientifically to be effective for the treatment of androgenetic hair loss. They are topical minoxidil for use in both men and women and oral finasteride for use in men," says Ms Chan Cheng Leng, Division Director of the Enforcement Branch of HSA. "The efficacy of complementary health products such as CPM and cosmetics is not assessed by HSA. As such, claims that such products can promote hair growth or slow hair loss may not be substantiated by scientific evidence," she added.

HSA also advised consumers to be wary of unrealistic or exaggerated claims on health products, particularly those that employ these gimmicks:

Promotions using terms such as "scientific breakthrough", "ancient remedy"

Testimonials from people claiming amazing results

Promises of no-risk, money-back guarantees

Promises of an easy fix

Claims that the product is "all natural" or "non-toxic"

Under the law, complementary health products are not allowed to contain western medicinal ingredients or substances controlled under the Poisons Act.

If convicted, offenders will be fined up to $5,000 and/or jailed for up to two years under the Medicines Act. They could also be fined up to $10,000 and/or jailed up to two years under the Poisons Act.

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